This article reports the findings of a study that attempted to elucidate whether pulsed magnetic energy stimulates neovascularization in vivo, using a microsurgically created arterial loop model in a prospective randomized trial of 108 rats (n = 12/group). Pulsed magnetic energies of 0.1 and 2.0 gauss were applied immediately postoperatively and for 4, 8, and 12 weeks, respectively, with a statistically significant increase in neovascularization among the treated animals compared with control rats. The study provides a starting point for future study and evaluation of the stimulation of angiogenesis with the use of pulsed magnetic energy and suggests a possible use of this modality to increase the quality of revascularized tissue.
Plast Reconstr Surg 2000 Apr;105(4):1371-4
Roland D, Ferder M, Kothuru R, Faierman T, Strauch B.
Department of Plastic and Reconstructive Surgery at the Albert Einstein College of Medicine, Bronx, NY, USA.