Category: research

Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates

Abstract Oxidative damage is implicated in several pathologies including cardiovascular disease. As a model system to study the response of cells to oxidative insults, homocysteine…

Effects of melatonin treatment in septic newborns

Abstract Free radicals have been implicated in the pathogenesis of neonatal sepsis and its complications. This study was conducted to determine the changes in the…

Pulsed magnetotherapy in Czechoslovakia-a review

Abstract Pulsed magnetotherapy has been used in Czechoslovakia for more than one decade. It has been proved that this type of physical therapy is very…

Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system

Abstract This review briefly summarizes the multiple actions by which melatonin reduces the damaging effects of free radicals and reactive oxygen and nitrogen species. It…

Possible therapeutic applications of pulsed magnetic fields [Czech]

Abstract Magnetotherapy is a relatively new, nowadays however, relatively widespread method in several medical disciplines. The mechanism proper of the favourable action of the pulsed…

Melatonin and its relation to the immune system and inflammation

Abstract Melatonin (N-acetyl-5-methoxytryptamine) was initially thought to be produced exclusively in the pineal gland. Subsequently its synthesis was demonstrated in other organs, for example, the…

The effects of pulsing magnetic fields on pineal melatonin synthesis in a teleost fish (brook trout, Salvelinus fontinalis)

Abstract Based on findings in various mammalian species, where exposure to electromagnetic fields decreased the nocturnal synthesis of the pineal secretory product melatonin, we investigated…

Beneficial effects of electromagnetic fields

Abstract Selective control of cell function by applying specifically configured, weak, time-varying magnetic fields has added a new, exciting dimension to biology and medicine. Field…

Melatonin: reducing the toxicity and increasing the efficacy of drugs

Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a molecule with a very wide phylogenetic distribution from plants to man. In vertebrates, melatonin was initially thought to be exclusively…

Potential biological consequences of excessive light exposure: melatonin suppression, DNA damage, cancer and neurodegenerative diseases

Abstract This brief review summarizes some of the biological effects of light exposure at an inappropriate time (during the normal dark period) and the potential…

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